THE SYNERGISTIC EFFECT OF MERCURY AND CADMIUM ON BLOOD PICTURE AND  CYTOGENETIC MATERIAL

J. Mutter, A.; N. Balasem, A.; K. Ali, A.

	THE SYNERGISTIC EFFECT OF MERCURY AND CADMIUM ON BLOOD PICTURE AND CYTOGENETIC MATERIAL
IRAQ JOURNAL OF AGRICULTURE
Article 1, Volume 14, Issue 5, 2009, Pages 0-0
Authors
A. J. Mutter; A. N. Balasem; A. K. Ali
Abstract
A Group of Liza abu were exposed to mixture of different concentrations of mercury and cadmium as followed 0.0083, 0.275 and 0.0165, 0.55 and 0.033, 1.1 and 0.048, 1.65 and 0.065, 2.2 ppm, respectively in addition to a non exposed control group. It was found that the median lethal concentration (Lc50) was 0.048, 1.65 ppm of mercury and cadmium, respectively for 48 hrs at 22c and pH 7.0 ±0.5. The micronuclei in red blood cells of exposed fishes were investigated as indirect measure for possible chromosomal abnormalities. Moreover, blood pictures including white blood cell count, red blood cell count, hemoglobin concentration and packed cell volumes, of exposed group of fishes were examined. A follow-up study for two groups of fishes exposed to 0.0083, 0.275 and 0.0165, 0.55 and 0.0033, 1.1 ppm of mercury and cadmium, respectively. The tests were carried out days, on the 10th, 20th, 30th and 60th of exposure. The numbers of white blood cells of fishes exposed to 0.33 and 1.100ppm of Hg and Ca was elevated within 30 days of exposure. It was returned to the normal value within 60 days of exposure. Meanwhile exposing fishes to 0.0165, 0.55 or 0.0033, 1.1 of Hg and Ca, respectively led to increase the frequency of micronuclei in red blood cells communing from the 10th days of exposure and was lasted for at least for 60 days in comparison with the control group. It seemed that an exposure of Liza abu to 0.0083, 0.275 ppm of Hg and Ca respectively did not induce micronuclei in red blood cells of exposed fishes.

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