- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
High Expression of P53 protein in Recurrent Pregnancy Loss Could Play a Role in the Pathology!! | ||
| Journal of the Faculty of Medicine | ||
| Article 1, Volume 53, Issue 2, 2011, Pages 194-197 | ||
| Authors | ||
| Thanaa Rasheed; B. Al-Obaidi; ; Nidhal Abdul-Mohaymen | ||
| Abstract | ||
| Background: Recent data provide evidence that p53 plays a critical role in mediating pregnancy by regulating steroid hormone activationObjective: localization of semi quantitation tof por protein at the materno-fetal interface, in patients with recurrent pregnancy loss. Methods: Immunohistochemistry analysis of p53 protein using paraffin embedded sections of curate samples obtained from 40 women, who where divided into three groups: 24 women with RPL, 10 women with abortion for the first time, and 6 women with induced abortion.Results: The mean value of the expression of p53 protein in the RPL group was (65.8±2.16), which is significantly higher than that of the second group (48.0±2.81), and the third group (50.0±4.66), (p=0.000).Conclusion: High expression of p53 protein in women with RPL may have a role in accelerating placental apoptosis leading to failure of pregnancy. | ||
| Keywords | ||
| recurrent pregnancy loss | ||
|
Statistics Article View: 78 PDF Download: 30 |
||