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Patterns of Clinically Isolated Syndrome in Patients Attending Multiple Sclerosis Clinic in Baghdad Teaching Hospital | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 12, Issue 1, 2015, Pages 66-79 | ||
| Authors | ||
| Wahab R. Ebdan; Firas khalifa Sharrad; Zaki Noah Hasan | ||
| Abstract | ||
| Clinically isolated syndrome (CIS) "is the first demyelinating event that is suggestive of multiple sclerosis and that makes patients at risk for further relapses". Eighty five percent of patients with multiple sclerosis, their onset is with (CIS). It is difficult to predict whether a given individual will develop multiple sclerosis following a (CIS). To determine pattern of (CIS) presentation among Iraqi patients and study factors associated with risk for conversion to clinical definite multiple sclerosis (CDMS). A record base study of thirty five patients labeled as (CIS) attending multiple sclerosis clinic in Baghdad Teaching Hospital was conducted during the period from 1/1/2011 to 1/12/2011. For each patient a study protocol sheet was done and filled from the database in the multiple sclerosis clinic, each patient was assessed clinically at least one time .The following information were studied: Patients gender , age at presentation , pattern of presentation , residual deficit after their 1st attack , disability depending on Expanded Disability Status Scale (EDSS), duration to convert to (CDMS) if they develop another attack after their diagnosis as (CIS), and their baseline MRI (1Tesla). The mean age for the studied sample is (34.20±8.38), with (9 male) and (26 female). A (28.6%) of the patients have multifocal and (71.4%) have monofocal presentation. Fifteen patients (42.9%) have residual deficit after their 1st attack , eleven patients (31.4%) converted to (CDMS), the mean time for conversion to definite multiple sclerosis is (23±15) months, six patients (17.14%) have normal brain MRI at their 1st presentation while the remainder have abnormal MRI. Conversion to (CDMS) is more in patient with multifocal presentation, residual deficit after 1st episode and positive baseline MRI findings. | ||
| Keywords | ||
| clinical isolated syndrome; pattern of presentation | ||
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