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Effects of Newcastle Virus Suspension on Some Organs of white Mice (Balb/C) | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 12, Issue 1, 2015, Pages 257-263 | ||
| Authors | ||
| Abbas Kadhim Al-Mansory; Ahmed Obaid Al-Zobaidy; Nemah H. Mehdi | ||
| Abstract | ||
| Newcastle disease is a contagious bird disease affecting wild avian species and many domestic, it may be transmissible to humans. Detection of Newcastle virus confirmed by rapid test technique (Immuno-chromatography). Ten samples (10%) out of 100 fasces samples collected from chickens were positive. Twelve mice used in this study divided into two groups, first group consist of six mice induced with 0.2 ml from one positive sample of Newcastle virus suspension to evaluate some histopathological changes in liver, lung and brain of mice, second group induced with 0.2 ml from phosphate buffer saline only. The results revealed that histopathological changes in liver were induced using 0.2 ml of Newcastle virus suspension ashyperpalsia in kufper cells. Lung of mice treated with this concentration of Newcastle virus has partial pnemonia and thickening the intra- alveolar walls. Brain of mice treated with same concentration induced increasing in number of glial cells (glialosis) and apoptosis in brain cells. | ||
| Keywords | ||
| Newcasstle virus; mice; Immunochromatography | ||
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