- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Flow Injection Spectrophotometric Determination of Thymol using 4-Aminoantipyrine and Copper(II) Nitrate | ||
| Baghdad Science Journal | ||
| Article 1, Volume 12, Issue 2, 2015, Pages 332-339 | ||
| Authors | ||
| Mouayed Q. Al-Abachi; Nada Ali Al-Najjar | ||
| Abstract | ||
| Flow-injection (FI) spectrophotometric method has been developed for the analysis of thymol in pharmaceutical preparations. The method is based on organic coupling reaction between thymol and 4-amino antipyrine in the presence of alkaline medium to form an intense stable red color complex with copper nitrate that has a maximum absorption at 490 nm. Optimum conditions for determination of the drug was investigated .The calibration graph was linear over the range of 5-500 µg.ml-1 of thymol . The limit of detection (LOD) and limit of quantification (LOQ) were 1.81 μg mL-1 and 3.60 μg mL-1 respectively .The proposed method was applied satisfactorily to the determination of thymol in mouth wash preparations. The procedure is characterized by its simplicity, accuracy and precision. | ||
| Keywords | ||
| Thymol; flow; injection Spectrophotometric determination; Aminoantipyrine; copper nitrate | ||
|
Statistics Article View: 156 PDF Download: 21 |
||