Evaluation of Some Biochemical Markers in Patient's with Polycystic  Ovarian Syndrome

T. O. Al-Jumaili, Farah; Jafar Naji, Aqeel; Mutlag Jasim, Thamer

	Evaluation of Some Biochemical Markers in Patient's with Polycystic Ovarian Syndrome
Jornal of Biotechnology Research Center
Article 1, Volume 9, Issue 2, 2015, Pages 37-45
Authors
Farah T. O. Al-Jumaili; Aqeel Jafar Naji; Thamer Mutlag Jasim
Abstract
The present study aims to detect several biochemical markers associated with PCOS (Polycystic ovary syndrome) in Iraqi women comparing the results with control normal fertile women and also studying the effect of obesity on the same biochemical markers. Ninety eight women with PCOS, 51 non-obese [body mass index (BMI) less than 25 kg/m2] and 47 obese (BMI >25 kg/m2) were enrolled for the study. Each group of them was compared forty normal fertile women as control group matched for each in age and BMI. The first part of this study was devoted to the measurement of Body Mass Index (BMI) and Waist Hip Ratio (WHR), subdivided PCOS according to the body mass index, and measurement of fasting insulin, fasting glucose, Homeostatic Model Assessment (HOMA), HbA1c and lipid profile. A significant differences was found in HbA1c (P≤0.0001) VLDL (p≤0.0001), triglyceride (p≤0.05) and cholesterol (p≤0.05) between obeses and lean PCOS patients. Insulin serum level (P≤0.0001) was highly significantly increased in obeses PCOS patients as compared to obeses control, the serum insulin (P≤0.0001) also significantly increased in lean PCOS women when compared with lean control. There was a significant differences between HOMA (P≤0.05) in obeses PCOS patients than in the obese control group and between obese and lean women PCOS patients.
Keywords
PCOS; Obesity; Obese Patients

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