Study the Relationship Between Obesity and Fertility in Diabetic Iraqi Men

Tahseen Nema Al-Aridhi, Dunia; I. Al-Ahmed, Hazim

	Study the Relationship Between Obesity and Fertility in Diabetic Iraqi Men
Jornal of Biotechnology Research Center
Article 1, Volume 9, Issue 2, 2015, Pages 81-88
Authors
Dunia Tahseen Nema Al-Aridhi; Hazim I. Al-Ahmed
Abstract
The aim of the present study is to investigate the relationship between obesity and fertility in Iraqi diabetic men whose body mass index (BMI) more than 25Kg/m2, and compare the results with control group corresponding age and BMI. Forty samples of men semen's were divided into two groups with and without diabetes and each group subdivided into two subgroups according to BMI. The parameters that measured in this study are( glucose, insulin and lipid profile in fasting state) also (testosterone, prolactin, alkaline phosphatase) were measured for each of four subgroups [controls(I, II) and diabetes(III, IV)]. Semen's analysis included (sperm concentration in ml, total count per ejaculate and viability). In diabetic subgroup (III) the mean levels of fasting blood glucose, insulin, cholesterol and triglycerides were significantly elevated, while significantly decrease in testosterone, prolactin, high density lipoproteins- cholesterol, alkaline phosphatase and total sperm count but there were no significant difference in total cholesterol, the sperm concentration and viability as compared with control subgroup(I). In diabetic subgroup (IV) the mean levels of fasting blood (glucose, insulin, cholesterol and triglycerides) were significantly elevated, while significantly decrease in (testosterone, prolactin, high density lipoproteins-cholesterol, alkaline phosphatase, sperm concentration, viability and total sperm count) but there were no significant difference in fasting (insulin and high density lipoproteins- cholesterol) as compared with control subgroup(II). In diabetic subgroup(III) the mean of BMI and the mean levels of fasting blood (glucose, total cholesterol and triglycerides) significantly elevated, while there were significantly decrease in(testosterone, alkaline phosphatase, sperm concentration, viability and total sperm count but there were no significant difference in fasting (insulin, high density lipoproteins- cholesterol) and prolactin, as compared with diabetic subgroup(IV). For all the above biochemical parameters investigated we can conclude that there is inverse- relationship between obesity and fertility which increase in the presence of diabetes.
Keywords
BMI; Obesity; diabetes mellitus; Fertility; Hormones; semen analysis; alkaline phosphatase enzyme

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