Correlation of Gonadel Hormones and Insulin Resistance with Seminal  Fluid in Infertile Males Afflicted with Diabetes Mellitus

M .J. AL-Shammaa, Nawal

	Correlation of Gonadel Hormones and Insulin Resistance with Seminal Fluid in Infertile Males Afflicted with Diabetes Mellitus
Al-Mustansiriyah Journal of Science
Article 1, Volume 26, Issue 1, 2015, Pages 24-31
Author
Nawal M .J. AL-Shammaa
Abstract
Male fertility requires normal sperm production and sperm transport, and adequate sexual performance, functions that require normal levels of testosterone. Male infertility could be due to number of factors, including abnormal spermatogenesis; reproductive tract anomalies or obstruction; inadequate sexual and ejaculatory functions; and impaired sperm motility. In this study, fifty men with type 2 diabetic aged under 40 years (31-39) and 50 non diabetic men with same age range as control. The mean age of the controls was (35 ± 3) years and of the diabetic patients (35 ± 4) years. The levels (Mean ± SD) of BMI, FBS, LH, FSH, prolactin, testosterone, C-peptide, IR, IS and seminal fluid count in control and patient groups were determined. A highly significant decrease of BMI in patients (ρ≤0.01) compared with the healthy control, and a significant decreased (ρ≤0.05) was noticed in seminal fluid count, LH, FSH, IS and testosterone levels, while a significant increase (ρ≤0.05) in FBS and C-peptide and IR levels was noticed. There was a no-significant increase in prolactin level in patient group compared with control. A negatively correlation was between seminal fluid count and BMI in control while it was positively correlation in patient group. Also, there was a positive correlation between seminal fluid count and FBS level in control group, while a negatively correlation noticed in patient group. A positively correlation between seminal fluid count and LH, FSH in control and patient groups. There was a positive correlation between seminal fluid count and prolactin control, whereas a negative correlation in patient group. There was a negative correlation between seminal fluid count and serum level C-peptide in each group. A positive correlation between seminal fluid count and IS determined in control and patient groups, while there was a negative correlation between seminal fluid count and IR in both.

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