Oral Glucose Tolerance Test (OGTT) among type 1 diabetic Siblings and Control group

Ali S. Al-Kabe, Muhamed; Kadem Al-Mousawi, Jaafar; Thamir Al-Kaabi, Kareem

	Oral Glucose Tolerance Test (OGTT) among type 1 diabetic Siblings and Control group
kufa Journal for Nursing sciences
Article 1, Volume 5, Issue 2, 2015, Pages 42-48
Authors
Muhamed Ali S. Al-Kabe; Jaafar Kadem Al-Mousawi; Kareem Thamir Al-Kaabi
Abstract
Background: the genetic factor of type 1 diabetes mellitus may play a key role in pathogenesis of that disorder, thus, diabetic siblings might prone into an impaired OGTT. Objective: To determine whether diabetic Siblings might have an impaired glucose tolerance test in compare to normal control group. Material and Method: A case-control study was performed on 120 persons, they divided into three group which are diabetic, siblings and control (40 persons in each group), who attended to Al Zahraa Teaching Hospital /Diabetic Center in Al Kut between the period from April; 2012 till April; 2013. Results: OGTT performed on both diabetic siblings and control, results have showed that the Means of OGTT is highly Significant (P value = 0.000) in both Siblings and Control groups, whereas there were no Significant differences in the Means of differences of OGTT in both tested groups (Siblings and Control), P value = 0.288, although the Mean of differences of OGTT is higher in Siblings group (25.3250) than that in Control group (22.0750). Conclusion: the inheritance factor play a key role in pathogenesis of type 1 diabetes mellitus since, diabetic siblings showed an impaired OGTT. Recommendation: for early detection of diabetes, diabetic siblings must submit to a routine screening test by OGGT.
Keywords
Type; Siblings; OGTT

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