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Erythropoietin level in acute leukemia | ||
| Iraqi National Journal Of Chemistry | ||
| Article 1, Volume 15, Issue 2, 2015, Pages 140-148 | ||
| Author | ||
| Seenaa Badr Mohammed | ||
| Abstract | ||
| Abstract Background: Acute leukemia is a proliferation of immature bone marrow-derived cells (blasts) that may also involve peripheral blood or solid organs. Erythropoietin, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production also has other range of actions including vasoconstriction-dependent hypertension, stimulating angiogenesis,and inducing proliferation of smooth muscle fibers. Objective: to evaluate serum level of erythropoietin in patients with acute leukemia. Research design and methods: In this case-control study, serum level of erythropoietin measured in 22 patients with Acute leukemia and 22 apparently healthy subjects using ELISA. Statistical analysis was performed using SPSS 17.0 . Results: There was a significant increment in level of erythropoietin in patients with acute leukemia compared to apparently healthy subjects (P < 0.001) independently to other parameters. Conclusion: Erythropoietin concentrations may predict adverse outcomes, and their measurement may facilitate risk estimation in leukaemic patients. | ||
| Keywords | ||
| KEYWORDS; erythropoietin | ||
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