Study the effect of Klebsiella pneumonia O-antigen as a immune catalyzer for laboratory rabbits infected with Entamoeba histolytica

M. Shakir, O.; N. Negres, O.

	Study the effect of Klebsiella pneumonia O-antigen as a immune catalyzer for laboratory rabbits infected with Entamoeba histolytica
Al-Anbar Journal of Veterinary Sciences
Article 1, Volume 7, Issue 2, 2014, Pages 66-81 PDF (981.13 K)
Authors
O. M. Shakir; O. N. Negres
Abstract
Conducted this study for the duration from the December 2013 until November 2014 and our study have included extracted outer membrane protein (O-Antigen) from Klebsiella pneumonia and study chireffection the immune response in Neusland albino rabbits (male) infected with Entamoeba histolytica that cause amoebic dysentery disease depending on several criteria, including study the changes in variables cytokineetics concentration levels that response on phagocytosis and antigen presenting process like IFN-γ, IL-10 and IL-12 and phagocytosis coefficienit, and B T cells PMNs and lymphocytes cell life span, the T and B rossite formation test the miotic index factor for bone marrow cell Arthus reaction, delayed hypersensitivity, measure the humeral immune response that responsting by immunoglobulins like IgG, IgM using ELISA Technic. And The current study accessed to elevated all immunity indicator after immunization with (k) antigen and also continue in elevation after the infection with parasite, and we indicated from this study the possibility to use the outer membrane protein (O antigen) that extracted from Klepsiella pneumoniae as immunological modificicatory that can stimulate both innate (natural) and acquired immunity against amoebic dysentery infection in white rabbit
Keywords
Rabbits; Klebsiella pneumonia; Klebsiella pneumoniae

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