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The Study of the effect of induced thyroid gland pathy on neutrophil activity in albino mice | ||
| Al-Anbar Journal of Veterinary Sciences | ||
| Article 1, Volume 8, Issue 2, 2015, Pages 40-45 PDF (515.49 K) | ||
| Author | ||
| L. H. Ali | ||
| Abstract | ||
| This study aimed to study the effect of induced hypo and hyper thyroid activity on the neutrophil activity. Thirty albino mouse was taken from Anbar University- College of Science. Animals were given food and water ad libitium and divided randomly into three groups each group contain 10 animals as follows: Control group: This group was subcutaneously injected with normal saline with dose 0.2 ml for 13 days. Second group was treated with carbimazole to reduce thyroid gland activity with 0.2 ml for 13 days. Third group was treated with thyroxin to increase thyroid gland activity with 0.2 ml for 13 days. At the end of treatment all animals blood was collected by heart puncture, blood was incubated with Nitrotetrazolium at 37 for 15 minute and smear was done and stained with Giemsa stain to study the activity of phagocytosis for all animal group. The result have shown a decrease in neutrophil percentage with decrease in their phagocytic activity in animal group treated with carbimazole, while an increase in the neutrophil percentage and their phagocytic activity in animal group treated with thyroxin. From these results it has been concluded that there is a direct relationship between thyroid hormone and neutrophil activity | ||
| Keywords | ||
| albino mice; thyroid gland; neutrophil | ||
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