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Study of pathological changes of experimentally Subacute selenium toxicity in Awasiy lambs | ||
| The Iraqi Journal of Veterinary Medicine (IJVM) | ||
| Article 8, Volume 38, Issue 1, 2014, Pages 20-25 PDF (0 K) | ||
| Authors | ||
| ; Al- Dulaimy; Al- Judi; ; ; S. A.G | ||
| Abstract | ||
| 10 Awasiy male lambs (4-6) month of age and body weight ranged between (16-26) Kg. ,were divided equally randomly to two groups ,1st group were subacute selenium toxicity and the 2nd group were control. Subacute selenium toxicity was induced by using sodium selenite as solution in daily oral dose for 8 weeks ,results of macroscopic examination to the 1st group revealed :ascitis ,hydropericardium ,flappy heart ,congestion of brain ,kidney and lung .As well as ,results of microscopic examination to the 1st group revealed in liver :acute cellular swelling ,degeneration and focal infiltration of neutrophils and inflammatory cells in the central vein .While the lung revealed :congestion ,dilation of alveolar capillaries and filled with blood and hyperplasia of lymphoid tissue and emphysema .While kidney revealed :degenerative changes ,congestion of blood vessels and medullary calcification .Brain revealed :demylenation .And spleen revealed :hyperplasia of white pulp and red pulp ,infiltration of neutrophils and congestion of blood sinuses .While the heart revealed :infiltration of lymphocytes and macrophages between muscle fibers .And the muscles revealed hyaline degeneration and infiltration of inflammatory cells .And the tongue revealed vacuolation of epithelium with multiple cellular aggregations surrounded by fibrous connective tissue capsule .While testis revealed complete suppression of spermatogenesis ,hydropic degeneration and vacuolation of spermatogonia if it is found. While the results of macroscopic examination to the 2nd group revealed no pathological singes noted ,and results of microscopic examination were normal .From all above this study concluded that toxicity of selenium effect negatively on meat health and so it will be not suitable for human consumption. | ||
| Keywords | ||
| Part of the Ph; thesis of the first researcher | ||
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