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DETECTION OF AUTO-ANTIBODIES SPECIFIC TO ISLETS CELLS INPATIENTSWITH THYROID DYSFUNCTION BY USING BIOCHIPSTECHNIQUE | ||
| Journal of Al-Nahrain University - Science | ||
| Article 1, Volume 12, Issue 3, 2009, Pages 133-138 | ||
| Author | ||
| Haider J.Muhammad | ||
| Abstract | ||
| AbstractThe aim of this study was to detect the auto immune Type 1 diabetes among the disorders withthyroid dysfunction (hyperthyroidism and hypothyroidism).The study included 50 patients sufferingfrom thyroid dysfunction, their aged was from (1-30) years. They were selected randomly from theAl-kindy center for infertility and indocrinology. The control group consisted of (20) healthysubjects comparable for age and sex of study groups. Thyroid function tests (thyroid-stimulatinghormone [TSH], thyroxin, and triiodothyronine) measured in by using miniVIDAS system andauto-antibodies for Beta cells in pancreas estimated in the same patients by usingimmunofluorescent method (IFAT), the method named BIOCHIPS Mosaic. Results of thyroidfunction test revealed that 25 patients were evaluated to have hyperthyroidism and 25 patients withhypothyroidism and the results of BIOCHIPS showed hyperthyroidism group was having autoantibodiesspecific to islets cells with 8 percent of all the subjects (two from 25 patients) .Whilethere was no signs of auto antibodies for islets cells in hypothyroidism group. The study revealedthat the prevalence of thyroid dysfunction was higher in women than men. | ||
| Keywords | ||
| hyper and hypothyroidism; autoimmune Diabetes Type; auto; antibodies islets cells | ||
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