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In vivo study of cherry stick effect on concentration of serum total cholesterol, triglyceride and total protein in white albino male mice | ||
| Journal of the Faculty of Medicine | ||
| Article 1, Volume 52, Issue 3, 2010, Pages 340-343 | ||
| Authors | ||
| Ahmed A. H. Al-Amiery; Arieg A.W. Mohammad; Maysoon M. Najeeb M. Saleem | ||
| Abstract | ||
| Background: Cherry extract has a wide range of biological activity. In the present investigation, two oral doses 0.04&0.08 mg/kg/day of cherry stick (ethanol extract) in albino male mice resulted in a significant decrease in concentration of serum total cholesterol concentration, triglyceride and total protein, albumin and globulin.Objective: we investigated the impact of biological activities of cherry stick extract on serum cholesterol, triglyceride, total protein, albumin and globulin in white albino male mice. Design: This study include three groups of white albino male mice. The first group (G1) was a control group comprised of 5 animals. The second group (G2) consisted of 5 animals treated with 1ml of cherry stick extract at concentration of 0.04 mg/kg/day for two weeks after treatment, while the third group (G3) consists of 5 animals treated with 1ml of cherry stick extract at concentration of 0.08 mg/kg/day for two weeks with treated animals.Results: there was a statistically significant reducing effect on serum total cholesterol, triglyceride, total protein and albumin P<0.001 at 0.04 mg/kg/day and 0.08 mg/kg/day for all biochemical parameters. Globulin was markedly decreased P< 0.01 in comparison with control but no significant change in ratio of albumin to globulin.Conclusion: Extract of cherry stick exerts at low dose a remarkable effect on serum cholesterol, triglyceride and total protein. | ||
| Keywords | ||
| Cherry; Cholesterol; triglyceride; Albumin and Globulin | ||
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