Effect of Nigella sativa seeds on the concentration of some plasma proteins

KADHI,; ALI AL, NAJDAT

	Effect of Nigella sativa seeds on the concentration of some plasma proteins
Diyala Journal For Pure Science
Article 1, Volume 10, Issue 3, 2014, Pages 65-80
Authors
; NAJDAT ALI AL
Abstract
The study was designed to investigate the effect of Nigella sativa seeds as crude and oil form on the concentration of some plasma proteins. forty eight male female volunteers (20-35) years old in Kirkuk city were included in the experiment .Twenty four of them received orally crude Nigella Sativa seeds 2gm/ day for six weeks. The other twenty four volunteers were received orally Nigella Sativa oil (NSO) 10ml/ day for six weeks. Blood were collected by vein puncture at the beginning of the treatment and considered as control and then at the end of second , fourth and sixth weeks of treatment and considered as treated groups . The serum were separated by centrifugation .Tests were carried out for measuring some serum proteins. Statistically significant differences between group means for control and treated values were identified with the use of analysis of variance (F-test). Results revealed that treatment of female volunteers by NSO increased the concentration of serum globulin and total protein at the end of fourth and sixth weeks of treatment significantly(p≤0.05) .The treatment of male volunteers by NSO increased the concentration of serum globulin and total protein at the end of sixth week of treatment significantly(p≤0.05). Treatment of volunteers with crude Nigella Sativa seeds increased the concentration of serum albumin in females at the end of the second and fourth weeks significantly(p<0.05) . Concentration of serum globulin and total protein in both sexes significantly increased(p<0.05) at the end of second week and continued to the end of the experiment. The globulin to albumin decrease significantly (p≤0.05) compared to control in both sexes with both types of treatment during different periods of treatment resulting from the increment of globulin levels. It is concluded that the treatment of volunteers with Nigella Sativa seeds as crude and oil fraction revealed to have a significant effect on serum proteins specially globulin and total protein during different periods . The crude form possesses more potent effect than oil fraction to in crease serum protein levels .
Keywords
Nigella sativa; plasma protein; cumin black seed; Nigella Sativa oil

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