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Novel synthesis and antibacterial activities of new derivatives of 7,8-Dichlorodibenzo(b, d)thiophene-2-carboxcyilic acid of pharmaceutical interest | ||
| Diyala Journal For Pure Science | ||
| Article 1, Volume 11, Issue 1, 2015, Pages 107-131 | ||
| Author | ||
| Ali .I. Mustafa | ||
| Abstract | ||
| Anew series of chemical compounds derived from 7,8-Dichlorodibenzo [b,d] thiophene-2-carbxylic acid were prepared. Reaction of 7,8-Dichlorodibenzo [b,d] thiophen-2-ethyl ester with hydrazine hydrate yields ,acidhydrazid. Dithiocarbzate prepared by reaction between carbon disulfide and carbahydrazide.4-amino-3-mercapto-1,2,4-triazole Prepared by reaction of thiocarbazate with hydrazine hydrate. Schiff bases prepared by reaction of 4-amino-3- mercapto-1, 2, 4-triazole with different substituted aldehydes. Seven membered ring compounds prepared by reaction of Schiff bases with maleic anhydride. The chemical structures of the products were characterized by (F.T.IR and 1H,13C. NMR), antibacterial activities of some of the prepared compounds were studied against four – kinds of bacterial. | ||
| Keywords | ||
| synthesis; antibacterial; Derivatives; Triazole; oxazenpine; Schiff bases; maleic anhydride; oxazepine | ||
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