synthesis and characterization of the amino complex of the silver nitrate )I( and studying its cellular toxicity in the Murine mammary adenocarcinoma Cell Line AMN-3

Zaki Lafta, Ahmed; Murad Hussian, Shalal; Abd-alrhman Ahmed, A; Safa,

	synthesis and characterization of the amino complex of the silver nitrate )I( and studying its cellular toxicity in the Murine mammary adenocarcinoma Cell Line AMN-3
Iraqi Journal of Cancer and Medical Genetics
Article 1, Volume 8, Issue 2, 2015, Pages 188-194
Authors
Ahmed Zaki Lafta; Shalal Murad Hussian; a Abd-alrhman ahmed;
Abstract
This study is synthesis involved the of amino complex of the silver ion )I(, and characterization , in molecular formula of the complex :[Ag)CMZ( NO3.H2O] that stands for CMZ-Carbamazepine .The prepared complex is identi ed by means of the infrared spectrum )FT-IR( and the Ultraviolet-visible spectrum UV-Vis , the atomic absorption, the accurate elementary analysis )C.H.N(, the molar electric conduct ability as well as the measurement of the melting degree. The study showed that the engineering con guration of all prepared complex is tetra-hedral .The effect of the complex is studied )In Vitro( on the Murine mammary adenocarcinoma Cell Line AMN-3. The decimal concentrations are begun at )1,10,100,1000,10000(μg/ml. So it is noticed there is no inhibition on the concentration )1,10,100(μg/ml. The ratio of inhibition is less than 50%. The study is concluded that there is a lethal toxical effect of the complex at the approved con- centrations: )1000,10000(μg/ml. The statistical horizontal comparisons among the concentrations of the complex exposure times , showed that the 24 hours, exposure to the concentrations)1000,10000(μg/ml. caused signi cantly affect )56,57.9% respectively( when compared with their corresponding concentrations of other exposure times.
Keywords
Silver amino complex; study

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