Mahdi Salman, S., K. Shneshil, M., Abdul Reda, W. (2016). Synthesis a Series of 1,3,4-Thiadiazole Derivatives and Investigate Their Biological Activity. , 12(1), 122-132.
Salih Mahdi Salman; Mustafa K. Shneshil; Waseela Abdul Reda. "Synthesis a Series of 1,3,4-Thiadiazole Derivatives and Investigate Their Biological Activity". , 12, 1, 2016, 122-132.
Mahdi Salman, S., K. Shneshil, M., Abdul Reda, W. (2016). 'Synthesis a Series of 1,3,4-Thiadiazole Derivatives and Investigate Their Biological Activity', , 12(1), pp. 122-132.
Mahdi Salman, S., K. Shneshil, M., Abdul Reda, W. Synthesis a Series of 1,3,4-Thiadiazole Derivatives and Investigate Their Biological Activity. , 2016; 12(1): 122-132.

Synthesis a Series of 1,3,4-Thiadiazole Derivatives and Investigate Their Biological Activity

Diyala Journal For Pure Science
Article 1, Volume 12, Issue 1, 2016, Pages 122-132
Authors
Salih Mahdi Salman; Mustafa K. Shneshil; Waseela Abdul Reda
Abstract
Eight compounds of new 1,3,4-thiadiazole biologically active for the series1,4-di(5-(4-substitutedphenyldiazenyl)-1,3,4-thiadiazol-2-yl) benzene were prepared through the reaction of terephthalic acid with thiosemicarbazide .The product was coupled with substituted benzene through a diazotization reaction. The synthesized compounds (2-9) were identified using the analytical and spectral means. The biological activity for those compounds was investigated against three types of bacteria Escherichia coli (Gram negative bacteria), Enterobacter (Gram- negative bacteria) and Staphylococusaurens (Gram-negative).
Keywords
Thiadiazol; biological active compounds; diazotization reaction
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