Study the Histological and Physiological Changes that Induced by Hydrogen Peroxide for Liver in Mice and the Role of Camel's Milk to Treatment

Shamil Hussien Al-Douri, Rasha

	Study the Histological and Physiological Changes that Induced by Hydrogen Peroxide for Liver in Mice and the Role of Camel's Milk to Treatment
Journal of Tikrit University For Agriculture Sciences
Article 1, Volume 16, Issue 3, 2016, Pages 1-8
Author
Rasha Shamil Hussien Al-Douri
Abstract
The purpose of this study was to evaluate the effect of camel’s milk on the mice liver after induction by hydrogen peroxide. Twenty albino mice were randomly divided into five groups A, B, C, D and E. (each group consisted of 4 mice), the first group was control, administrated only normal diet and water. The second group was administrated with 1% of H2O2. The third group was administrated with 1.5% H2O2. The fourth group was administrated 1% H2O2 and treated with camel milk for 15 days and the fifth group was administrated 1.5% H2O2 and treated with camel milk for 15 days. The Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) levels were increased and showed high significant changes (P < 0.01) in groups that administrated H2O2 only compared with control group and also the liver tissue showed different lesion including necrosis, degeneration of hepatocytes, infiltration of lymphocytes, sclerosing bile ducts and fibrosis, but when these groups treated with camel milk, the ALT and AST levels return to the normal ranges and the liver tissue became normal and repaired completely. It was concluded from this study that the camel milk has amply good effect on the liver enzymes and tissue repair.
Keywords
Histological; physiological changes; hydrogen peroxide; liver; mice; Camel

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