Experimental and Acomparative Study for the effect of GlucosAmine hydrochloride as  Antioxidant in Sera of Adult Male Rabbits

Razooq Hameed Al- Samarrai, Rafah; Mohamad Hashem Al-mulisy, Arwa

	Experimental and Acomparative Study for the effect of GlucosAmine hydrochloride as Antioxidant in Sera of Adult Male Rabbits
Tikrit Journal of Pure Science
Article 1, Volume 21, Issue 2, 2016, Pages 85-97
Authors
Rafah Razooq Hameed Al- Samarrai; Arwa Mohamad Hashem Al-mulisy
Abstract
This study involved giving the administration of Glucosamine hydrochloride to (Adult Male Rabbits) through the feeding tube .Was used in this experiment (21) Rabbit were distributed randomly into three groups . Group is control to each containing This study involved giving drug glucoseamine hydrochloride Secretary of the animals used in the experiment (rabbits adult males ) through the feeding tube as used in this experiment 21 animals were distributed randomly into 3 groups of 7 rabbits per group . Treated the first two sets glucoseamine hydrochloride doses of 70 and 9 mg / dl / day group first and second , respectively, for a period of 30 days, while the third group used Xatrh treated with saline Physiological was then assess the property on each of the antioxidants and the image of the fat and some liver enzymes in the blood , as well as liver tissue . The results showed that the significantly increased of the GPX morally P ≤ 0.05)) in the group G1 compared with C, either GSH significantly increased when the G2 compared to control , also showed MDA increased significantly for both groups compared with C, while showed peroxy nitrit have decreased significantly, with no significantly change in uric acid. The level of TG was significantly lower with C , while the cholesterol the same results when the G1 compared with C, either LDL-C and sessile density has increased significantly compared with C, HDL-C levels significantly elevated sera of G1 only, but in the G1 also , decreased the level of VLDL compared with C . The liver enzymes AST enzyme has shown a significant increase compared with C. with no significantly change in both ALT, ALP, total protein, albumin and Globulin any significant effect compared with the C group, also showed the results of the study tela affected liver tissue of the two groups , as results showed infiltration of the cells of the lymph cells Kuppffer cell around the central vein congested G1, with necrosis in a vein in the G2.

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