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Study the relationship between Apelin and some biochemical parameters in patients with kidney diseases | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 21, Issue 7, 2016, Pages 110-118 | ||
| Authors | ||
| Mousa J. Humaish; AbduL-Monaim H.M. AL-Samarrai; Noor I. AL-Samarrai | ||
| Abstract | ||
| The study aimed to determine the effect of the lack of peptide apelin in the pathogenesis of kidney patients and the positive impact when increasing its concentration in the body and protect the body from various diseases. The study included 57 patients of different ages and were compared with the control group, which included 25 samples.Through the study, which was conducted and when measuring the concentration of Apelin show that there is a significant decrease (P≤0.01) at a concentration of Apelin in people who suffer from kidney disease compared with the control group, which was Apelin concentrations with in the normal range, and it has been Measuring range of biochemical variables to find a statistically significant correlation between their concentrations and the concentrations of Apelin and results of the study follows :The concentration of nitrogen compounds and their relationship with Apelin levels: found high significant (P≤0.01) at each concentration of urea, creatinine and uric acid in people who are suffering from various kidney diseases compared with the control group, which was within normal of biochemical variables. And their relationship was a correlation with the concentration of Apelin is an inverse relationship. The concentration of proteins in the blood serum concentrations and their relationship Apelin: found a significant increase (P≤0.01) in the concentration of each of the total protein and globulin in people suffering from various kidney disease compared with the control group, which was within normal concentrations of the protein that resides in the body, While the results did not show any significant differences in the concentration of albumin between patients and control group. and their relationship with apelin concentration is an inverse | ||
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