Study The Effect of Some Content of Pomegranate Fruit in Inhibition of Atherosclerosis and Reduce Oxidative Stress in Rat

Ibrahem Hasan, Noor; Mohamad Mubark, Zaid

	Study The Effect of Some Content of Pomegranate Fruit in Inhibition of Atherosclerosis and Reduce Oxidative Stress in Rat
Journal of Tikrit University For Agriculture Sciences
Article 1, Volume 16, Issue 4, 2016, Pages 40-51
Authors
Noor Ibrahem Hasan; Zaid mohamad Mubark
Abstract
The current study was designed to investigate the effect of Juice and Aqueous Extract of Pomegranate (Punica granatum)on Atherosclerosis that induced by adding cholesterol to the ration at a dose of (130 mg/ Kg ration). furthermore study the effect of Juice and aqueous Extract on oxidative stress that induced by using Hydrogen Peroxide at a dose of (0.05%) with drink water, Twenty eight adult rats were used in this study from male and female aged (3-5) months randomly divided in to( 7) groups (4 animals/ group) These group are The control group, H2O2 group, Pomegranate Juice and H2O2 group, pomegranate aqueous extract and H2O2 group, cholesterol group, Pomegranate Juice and cholesterol group, Pomegranate aqueous extract and cholesterol group ,measure some physiological and biochemical parameters like count of (WBCs), concentrations of (Hb),Total count of (RBCs),packed cell volume (PCV),(TC),(TG),Atherogenic indices levels in the serum of White Rats. The result Showed the treatment of H2O2 with the juice and the treatment of cholesterol with juice increased significantly( P <0.05) in the total number of W.B.C when compared to control , did not show the treatment of cholesterol with Abstract significant differences with get significant increase in WBCs in the treatment of H2O2 with the Abstract and the treatment of cholesterol with Abstract , the results showed a significant decrease (P <0.05) in RBCs and WBCs and HB and PCV in the treatment of H2O2 and the treatment of cholesterol when compared to the control , showed the treatment of cholesterol with juice increased significantly in the number of red blood cells while it did not appear the treatment of H2O2 with juicy significant differences when compared with the control , resulted in the treatment of animals with extract of pomegranate to get significant decrease in the concentration of RBCs in the treatment of H2O2 did not show the treatment of cholesterol with Abstract significant differences , showed the treatment of H2O2 with the Abstract and the treatment of cholesterol with Abstract increased significantly in the PCV when compared to the control , showed the treatment of H2O2 with the juice and the treatment of cholesterol with juice increased significantly in the size of blood cells stacked when compared to control . The results of the study for significant decrease in the concentration of total cholesterol and Alklsaredat triple in the treatment of H2O2 with the juice and the treatment of cholesterol with the juice when compared to the control , as shown by the results of the study for significant increase in the level of Altasd first , second and third in the treatment of H2O2 and the treatment of cholesterol results showed for significant decrease in Altasd level I, II and III in the treatment of H2O2 with Abstract and treatment with cholesterol extracted with additional significant decrease in the concentration of total cholesterol and triglycerides Alklsaredat treated with the extract and H2O2 treatment with cholesterol Abstract
Keywords
WBC; Haemoglobin; RBCs; Total holesterol; triglyceride; hydrogen peroxide; PCV

Statistics Article View: 29 PDF Download: 9