College of medicine-Baghdad University, A., research Unit, H., Hyam Raouf, D. (2016). Association between HLA and Guillain Barre' syndrome. , 12(1), 109-111.
Al-Kindy College of medicine-Baghdad University; HLA research Unit; Dr. Hyam Raouf. "Association between HLA and Guillain Barre' syndrome". , 12, 1, 2016, 109-111.
College of medicine-Baghdad University, A., research Unit, H., Hyam Raouf, D. (2016). 'Association between HLA and Guillain Barre' syndrome', , 12(1), pp. 109-111.
College of medicine-Baghdad University, A., research Unit, H., Hyam Raouf, D. Association between HLA and Guillain Barre' syndrome. , 2016; 12(1): 109-111.

Association between HLA and Guillain Barre' syndrome

Al-Kindy College Medical Journal
Article 1, Volume 12, Issue 1, 2016, Pages 109-111
Authors
Al-Kindy College of medicine-Baghdad University; HLA research Unit; Dr. Hyam Raouf
Abstract
Background: Genetic factors play an important role in susceptibility to Guillain Barre' syndrome. Human leukocyte antigen (HLA) as part of immune system has a role in the disease process.
Aim of the study: to assess the relationship between HLA-A alleles with Guillain Barre' syndrome (GBS) compared with a healthy control group using PCR-SSOP method.
Type of the study: Cross-sectional study.
Patients and methods:Patient's group consisted of 30 Iraqi Arab Muslims patients with Guillain Barre' syndrome that consulted the Neurological department in Neurosciences Hospital between January-2013 to January- 2014 were genotyped for HLA-A alleles. A control group consisted of 30 healthy volunteers among the staff of AL-Kindi College of Medicine that did not have any neurological disorders.
Results: Present study found a decreased frequency of HLA-A:0101 allele (p=0.001) in GBS patients compared to healthy controls.
Conclusions: current results suggest that GBS is negatively associated with HLA-A:0101 allele.
Keywords
Key Words; HLA; PCR
Statistics
Article View: 159
PDF Download: 70


Journal Management System. Powered by iJournalPro.com