Study of prodigiosin and virulence factor producing by multi drug resistance Serratia marcescens isolated from some of Baghdad hospitals environmen

Mun,; R. Ali, Im

	Study of prodigiosin and virulence factor producing by multi drug resistance Serratia marcescens isolated from some of Baghdad hospitals environmen
Al-Mustansiriyah Journal of Science
Article 1, Volume 19, Issue 5, 2008, Pages 1-9
Authors
; im R. Ali
Abstract
Serratia marcescens were detect in (398) swap samples from Baghdad hospitals environment, detection depending on culture & microscopical characteristics of bacterial cell & Biochemical tests and to be ensure by using api20E, was done to find (9) isolates belong to Serratia marcescens. The antibiotic sensitivity test was done against (14) different antibiotics, the isolates showed multiresistant against (4-8) antibiotics, all isolates were resistant by (%100) against Cefuroxime ,Cefixime ,Cephalothin and Penicillin, while Cephotaxime ,Azteroname ,Imipeneme and Ciprofloxacin were sensitive by (%100).All isolates were tested to have β-lactamase production by Iodo metric method , the results showed 5 isolates ( %55.55) able to produce the enzyme. while all isolates were able to produce other enzyme such as DNase, Protease, Esterase and Lipase .there are 4 isolates(44.44) were able to adhere to the epithelial cells. Prodigiosin production was seen at 28°C in nutrient broth. At 30°C Serratia marcescens show optimam pigment production in peptone glycerol broth. Therefore, this study leads to increase Serratia marcescens survival ability in hospital environments and resistance to most antibiotics in addition to many potent virulence factor productions. That leads to increase it's important as opportunistic pathogen. And shade the light on the Prodigiosin production. At 30°C, pigmented Serratia marcescens strain make read colonies via the production of Prodigiosin on different culture media. At 37°C, the bacteria growth well, but make

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