Determination of some biochmecal markerd in patients with breast cancer

Abd Almunim Baker, Luma

	Determination of some biochmecal markerd in patients with breast cancer
Tikrit Journal of Pure Science
Article 1, Volume 19, Issue 5, 2014, Pages 27-31
Author
Luma abd almunim baker
Abstract
Abstract Breast cancer is a big problem in Western females in which the most useful serum markers of this diseases in its early stage are CA15-3and CEA.CA125play a big role with other physical examination in the detection of ovarian cancer ,but its role with breast cancer has been studded with this research beside the effect of Creactive protein (CRP) as the aim of this study46 consecutive women suffering from breast cancer and aged from 35-45 years has been included in this study.CA125 were investigated by minividas. C.R.P. was measured also using a fresh sera by C.R.P. latex test C.A125 and C.R.P. levels were measured every three months interval to follow up the patient before each course of chemotherapy the results showed the mean ± SD for CA125 before chemotherapy was 65.78 ± 15.68 which was shown significant differences with the first (54.76 ± 12.44) , second (50.15 ± 11.62) and third month (40.02 ± 10.13) of chemotherapy with P<0.000 . C-Reactive protein was measured also for all patients for the same period of time . There is a significant differences in the concentration of C.R.P. between group 1(96&48 mg/dl) and group 2 (<6,12,24 mg/dl) in the 1 st month p<0.0001 -p<0.0002 in the 2nd month and p<0.0001 in the 3 rd month The results of these calculations the future it may be useful if we research about a relation between these two parameters (CA125 & CRP) in the case of metastasis of breast cancer .

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