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Synthesis of Some Mixed ligands Complexes of (2-hydroxy benzaldine)-4-amino Antipyrine and 1,10-phenanthroline and Studying their antibacterial activity | ||
| Baghdad Science Journal | ||
| Article 1, Volume 14, Issue 1, 2017, Pages 39-47 | ||
| Authors | ||
| Mahasin F. Alias; Israa H. Ibraheem; Maysoon M. A bdul Hassan | ||
| Abstract | ||
| Complexes from the ligand (2-hydroxy benzaldine)-4-aminoantipyrine with some transition metal ions V(lѴ),Cr(lll),Fe(lll) and Co(ll) were prepared in the presence of the co-ligand 1,10-phenanthroline in alcoholic medium. These compounds were characterized by the available techniques: FT-IR ,UV-Visible ,magnetic susceptibility, Flame atomic absorption technique as well as elemental analysis and conductivity mesurments .From these spectral studies, a square pyramidal structure proposed for V(IV) complex and an octahedral geometry for Cr(III),Fe(III) and Co(II) complexes. The biological activity of the ligands and their complexes were evaluated by a gar plate diffusion technique against three human pathogenic bacterial strains: Pseudomonasaerogenuosa,E.schriachia coli. and Staphlococcus arureus. Some of the complexes were found to have a good antibacterial activity a gainst these pathogens | ||
| Keywords | ||
| mixed ligand; hydroxybenzaldine; aminoantipyrine; phenanthrolin; Schiff Base; biological activity | ||
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