Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal Candidiasis

Mohammad Abd AL-khaliq Msc, Israa; Mohammad Jasim MSc, Rusul

	Inhibitory Effect of Aqueous Salvia officinalis’s leaves in the Growth of Candida albicans from Infected Women with Vaginal Candidiasis
Al-Kindy College Medical Journal
Article 1, Volume 7, Issue 1, 2011, Pages 47-49
Authors
Israa Mohammad Abd AL-khaliq Msc; Rusul Mohammad jasim MSc
Abstract
Background : Salvia officinalis is a plant belong to Labiatae family .The common name of Salvia is sage which mean save. The leaves of Salvia have special oil which is effective against filamentous fungi and yeasts such as Candida albicans which is the causative agent of vaginal candidiasis in women Methods . Cultures from 50 swabs of Candida albicans isolated from vagina of 70 patient women who complains from vaginal problems, their ages (24-43) years from Central City Hospital during Febreoury 2009 to April 2009 were cultured on Sabouraud Dextrose Agar (SDA) .Nystatin was used as positive reference standard to determine the sensitivity of this fungus . and less this concentration there was no minimum inhibition for the Candida Results : The aqueous extract of Salvia officinalis at various concentrations inhibited the growth of C. Albicans . This inhibitions reached to a maximum of 100% for extract at 25 mg / ml and the minimum inhibition was 170 mm at 15 mg /ml for the extract . While the minimum and maximum inhibition for nystatin was at 50 µg/ml,and less concentration. There was no minimum inhibition for the Candida Conclutions : The findings provide support for the use of this plant in traditional medicine for fungal infections especially against candidiasis .
Keywords
Antifungal activity; Candida Albicans; Nystatin; Salvia officinalis; Vaginal candidiasis

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