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Synthesis and biological evaluations of new phenothiazine derivatives | ||
| journal of al-qadisiyah for pure science(quarterly) | ||
| Article 1, Volume 15, Issue 3, 2015, Pages 42-51 PDF (0 K) | ||
| Author | ||
| Muqdad Irhaeem kadhim | ||
| Abstract | ||
| This work includes synthesis of new derivative of phenothiazine , in order to obtain these derivatives ; chalcone 3 was subjected to a Aldol condensation reaction between 10-ethyl-3- phenothiazin-3-yl carbaldehyde , this compound was reacted with some different reagent such as hydrazine hydrate , phenyl hydrazine , thiosemicarbazide and hydroxyl amine to give pyrazolines 5,6,7,8 and oxazoline 9 . The structures of all the compounds were confirmed by microanalyses and various spectral data . the synthesized new compound were screened against antimicrobial activity | ||
| Keywords | ||
| Synthesis and biological evaluations of new phenothiazine derivatives | ||
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