Antifungal Activities of Alcoholic and Aqeuous Extracts of punica granatum against Some Non-Dermatophytic Fungi

Lecturer,; Naeem Abbas, Faten

	Antifungal Activities of Alcoholic and Aqeuous Extracts of punica granatum against Some Non-Dermatophytic Fungi
Thi-Qar Medical Journal
Article 1, Volume 7, Issue 1, 2013, Pages 101-119
Authors
; Faten Naeem Abbas
Abstract
ABSTRACT: A clinical and mycological study of superficial mycosis was conducted on 23 cases (7 males and 16 females) , and collected from patients (5-50) years old. Direct microscopy by KOH (potassium hydroxide) mount and culture was undertaken to isolate the fungal pathogen in each case. Non-dermatophyte molds were isolated from 18 cases (78.26%) and 21 isolates were identified from these cases ; 10 isolates Candida albicans (47.61%), 5 isolates Rhizopus stolonifer (23.8%), 2 isolates Penicillium sp. and 2 isolates Aspergillus nidulans (9.5%) respectively, 1 isolate Alternaria alternata and1 isolate Fusarium sp. (4.7%) respectively . Alcoholic & aqueous extracts of the punica granatum (Pomegranate) peels were prepared. The anti-fungal activity of the extracts was evaluated on isolated fungi by means of the agar-well diffusion assay. The Minimum inhibitory concentrations were 10-300 mg/ml against isolated fungi. Their was little difference between the activities of alcoholic extract & aqueous extract. These results suggest the Pomegranate Peels extract which contains active constituents as a promising anti-fungal agent.

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