SYNTHESIS AND CHARACTERIZATION OF COMPLEXES OF CO(II), NI(II), CU(II)AND ZN(II) WITH MANNICH BASE LIGANDS DERIVED FROM PIPERAZINE AND ITS BIOLOGICAL ACTIVITY

H. SHEHAB, OMAR; S. AMER, AYAA

doi:10.37652/juaps.2014.123983

	SYNTHESIS AND CHARACTERIZATION OF COMPLEXES OF CO(II), NI(II), CU(II)AND ZN(II) WITH MANNICH BASE LIGANDS DERIVED FROM PIPERAZINE AND ITS BIOLOGICAL ACTIVITY
Journal of University of Anbar for Pure Science
Article 20, Volume 8, Issue 2, 2014, Pages 84-90
Document Type: Research Paper
DOI: 10.37652/juaps.2014.123983
Authors
OMAR H. SHEHAB; AYAA S. AMER
Collage of Education for Women- University of Anbar
Abstract
The complexes of manch base (derived from Salicylaldehyde and represented by L1:(1,1-(piperazine-1,4-diylbis((2-hydroxyphenyl)methylene))di urea L2:(N,N-piperazine-1,4-diylbis((2- hydroxyphenyl)methylene))dithiourea with transition metal salt of Zn(II), Co(II), Ni(II) and Cu(II) were prepared . They were characterized by using (FT-IR) spectroscopy,(UV-Vis.) spectrophotometery, also by using molar conductance . This study showed that ligands as a chelating bidentate and the Co , Zn complexes have an octahedral geometry, and the Cu , Ni complexes have square planer and tetrahedral geometry respectively. The free ligands and their complexes have been tested for their antibacterial activities against two kinds of human pathogenic bacteria: (Staphylococcus aureus), (Escherichia coli ). The first group are Gram positive while the second group are Gram negative by using agar well diffusion method. Finally , it was found that compounds show different activity of inhibition on growth of the bacteria.

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