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Synthesis, Characterization and Biological Investigation of Some New Hydroxy – 1,3,4 – Oxadiazole Derivatives | ||
| Kirkuk Journal of Science | ||
| Article 1, Volume 11, Issue 3, 2016, Pages 304-320 PDF (962.33 K) | ||
| DOI: 10.32894/kujss.2016.124650 | ||
| Authors | ||
| Afraa S. S; Jawdat H. A | ||
| Abstract | ||
| study the solid compounds of hydroxy 1,3,4 – oxadiazoles have been synthesized by reaction of acid hydrazides with CS2 in the presence of KOH. All the prepared compounds are characterized by using elemental analysis (C, H, N and S) and spectroscopic IR, H1 – NMR and studied the biological activity on four antibacterial (gram +Ve and gram –Ve) and three antifungal organisms. 1,3,4 – Oxadiazole are important compounds because of its versatile biological action such as antimicrobial, antimalarial, anticonvulsant, hypoglycemic, also analgesic, anti – inflammatory and anticancer. In the present | ||
| Keywords | ||
| oxadiazole; hydroxyl phenyl oxadiazole and biological activity of oxadiazole | ||
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