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Evaluation of lipid fractions in serum of premenopausal and postmenopausal women in Kirkuk city | ||
| Kirkuk Journal of Science | ||
| Article 1, Volume 12, Issue 1, 2017, Pages 141-155 PDF (0 K) | ||
| DOI: 10.32894/kujss.2017.124968 | ||
| Authors | ||
| Najdat Ali Shafik; Fatma Mustafa Mohammed; Ektefa Abdulhameed | ||
| Abstract | ||
| The study aimed to investigate the levels of lipid fractions in the serum of premenopausal and postmenopausal women in Kirkuk city, because an alteration of there concentrations considered an important predisposing factors for incidence of cardiovascular disease . The study included 100 premenopausal women raged age 27- 45 years and 90 postmenopausal women ranged age 51- 67 years. The blood samples were collected and centerfuged for determination of total cholesterol( TC ) , triglyceride( TG ), low density lipoprotein( LDL-C ), high density lipoprotein( HDL-C), and very low density lipoprotein ( VLDL-C ) concentrations .The results of the study revealed no significant differences ( p>o.o5 ) for TC level, but there was a significant increase ( p<0.05 ) in the level of TG in postmenopausal women ( 143.13 ± 38.14 ) mg/dl When compared with the premenopausal women ( 102.88 ± 34.11 gm/dl. While concentration of HDL-C recorded a significant decrease ( p<0.05 ) in postmenopausal women ( 33.01 ± 10.22 ) mg/dl, when compared with the premenopausal women ( 42.20 ± 15.24 ) mg/dl, also the same results recorded for LDL-C concentration ( 106.55 ± 23.2 ) mg/dl in postmenopausal women and ( 76.26 ± 32.06 ) mg/dl in premenopausal women. Whereas the significant increase ( p<0.05 ) in concentration of VLDL-C ( 31.63 ± 7.64 ) mg/dl in postmenopausal women when compared with the premenopausal women ( 20.58 ± 6.82 ) mg/dl. Finally we concluded that, there was a significant alterations in the level of lipid profile between premenopausal and postmenopausal women groups ,which were considered the most critical predisposing factor for incidence of cardiovascular disease in postmenopausal women. | ||
| Keywords | ||
| Lipid profile; premenopause; postmenopause; Cardiovascular disease | ||
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