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Iron Deficiency Anemia: The Utility of Upper GastrointestinalEndoscopy and Histopathology | ||
| Al-Kindy College Medical Journal | ||
| Article 1, Volume 4, Issue 1, 2008, Pages 43-46 | ||
| Authors | ||
| Ali M Al-Doori PhDHematol; Yaseen H Al-Dulaimi; Adnan MH Al-Hamwandi | ||
| Abstract | ||
| Background: occult blood loss must be considered as a possible cause in every case of iron deficiency anemia.Objective: to evaluate upper gastrointestinal endoscopy in finding a potential cause for iron deficiency anemia among children in Al-Anbar governorate.Methods: Twenty five children aged 2-14 years, referred to the gastroenterology unit in Al-Ramadi General Hospital for upper gastrointestinal endoscopy had iron deficiency anemia. Fiberoptic endoscopy was used under general anesthesia and endoscopic tissue biopsies were taken from 22 patients for histopathological examination.Results: The main presenting signs and symptoms were pallor, abdominal pain, and stunting. The upper gastrointestinal endoscopy showed thinning of duodenal folds & serrated mucosa in 8 (32%), duodenal ulcer in 3 (12%), esophageal varices in 1 (4%), nodular gastritis in 1 (4%), and reflux esophagitis in1 (4%), with a yield rate of 56%.While tissue biopsies revealed histopathological findings suggestive of celiac disease in 12 (48%), Giardia lamblia in 2 (8%), Helicobacter pylori gastritis in 1 (4%), and esophagitis in 1 (4%). There was a significant association between the endoscopic finding of thinning of duodenal folds and serrated mucosa and the histopathological finding suggestive of celiac disease, P<0.05.Conclusion: Iron deficiency anemia in children 2-14 years of age warrants upper gastrointestinal endoscopy to find potentially treatable causes for the iron deficiency anemia.Key words: Children; Iron deficiency anemia; Upper gastrointestinal Endoscopy. | ||
| Keywords | ||
| Children; Iron deficiency anemia; Upper gastrointestinal Endoscopy | ||
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