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Comparison of amelogenin sub-proteins osteoinductive activity (Histopathological study) | ||
| Journal of baghdad college of dentistry | ||
| Article 1, Volume 20, Issue 1, 2008, Pages 24-27 | ||
| Author | ||
| Riyadh O. Alkaisi | ||
| Abstract | ||
| ABSTRACTBackground: Enamel matrix proteins (EMP) represent one of the most effective members of the bone morphogenic protein (BMP) family.Materials and methods: Chemical isolation of AM followed by isolation of AM sub-proteins was done using gel filtration chromatography and polyacrylamide gel. Beside that the histopathological pictures after the application of each AM sub-proteins in a bony defect created in the mandible of hamsters were observed.Results: Only the intermediate molecular weight sub-protein (application showed a rapid healing process and new bone formation.Conclusions: Among the 3 AM sub-protein only the intermediate one represents the bone morphogenic factor.Key words: Enamel matrix proteins, AM sub-proteins. (J Bagh Coll Dentistry 2008; 20(1)24-27) | ||
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