Toxoplasmosis disease and its association with hepatic enzymes

Fadhel AL-Kazzaz, Fatin

	Toxoplasmosis disease and its association with hepatic enzymes
journal of al-qadisiyah for pure science(quarterly)
Article 1, Volume 11, Issue 2, 2011, Pages 33-40 PDF (0 K)
Author
Fatin Fadhel AL-Kazzaz
Abstract
In this study, 120 women with history of abortion were subject to serological tests (ELISA test) to trace cases of Toxoplasmosis. The IgG &IgM antibodies were increase (p<0.05) in the sera of women with toxoplasmosis in the percent 17.5% for IgG, 3.3% for IgM and 1.6% for IgG&IgM antibodies. The highest rate of positivity was recorded in women who suffered from abortion with age of (26-35) age group 56.3%, while the lest rate of seropositivity was recorded in women with age of (36-45) age group was 16.4%. The levels of liver enzymatic including Aminotransferases (ALT & AST) and Alkaline Phosphates (ALP) were measured in the toxoplasmosis seropositive women and compared to their respective mean values in the sera of seronegative women, the mean levels of ALT & AST and ALP were significant elevation p<0.05 in the seropositive women in comparison to the seronegative women. Moreover, there were no significant elevations in the levels of the studies biochemical parameters within the age groups of toxoplasmosis seropositive women and seronegative women. In conclusion, the concomitant rise of the serum enzymes activities and the associated changes in the levels of IgG & IgM antibodies. This process might be incriminated for the host tissue infestation by this parasite which has the ability to survive in the host cells and tissues for life and that may gives to the repeated abortions.

Statistics Article View: 110 PDF Download: 89