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Effect of prostaglandin (F2 α) on TSH and Thyroid hormone (T3 & T4) in an endemic rabbit males Oryctolacus caniculu | ||
| journal of al-qadisiyah for pure science(quarterly) | ||
| Article 1, Volume 10, Issue 3, 2010, Pages 44-51 PDF (0 K) | ||
| Authors | ||
| Haider Kamil Zidan; Shaymaa Obied Abdella | ||
| Abstract | ||
| This study aimed to investigation the role of PG F2α on levels of thyroid stimulating hormone (TSH) & thyroid hormone (T3 & T4) . The experiment was conducted on (16) adult male of domestic rabbits , it's weight to range between (1.855 – 1.960) kg and it's age between ( eight months – one year) . The animals were given PG F2α subcutaneous daily for ten days within used amounts (10 ,20, 30) µg /kg of body weight . The animals is killed after (24 ) hours from the last dose of treatment . The blood sample were collected from heart ( by heart puncture ) for measured of hormones levels . The results reveal followed when comparison with control group : 1- A significant increase (P<0.01) in thyroid stimulating hormone (TSH) level 2- There is increase (not reach for significant level) in triiodothyronine (T3) level. 3- There is significant increase( P< 0.05) in thyroxin ( T4 ) level in groups which treatment with (10 ,20 ) µg /kg while the increase not significant in group that treatment in(30) µg /kg . | ||
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