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Detection of Immunomodulatory activity of alcoholic extract ofCordia myxa(L.) fruit | ||
| journal of al-qadisiyah for pure science(quarterly) | ||
| Article 1, Volume 10, Issue 4, 2010, Pages 14-21 PDF (0 K) | ||
| Authors | ||
| a A.A.Ad-Dahhan; | ||
| Abstract | ||
| This study was doing to detect the medically active compounds and ethanolic extract of Cordia myxa(L.) fruits,since this plant considers one of the medically important plants, which is widely used for treatment of numerous diseases .The toxicity of this extract to immunological cells (lymphoid & phagocyte)was evaluated and different concentrations of extract were prepared .the percentage of cytotoxicity was inhibited significantly (P<0.05) with increase the concentration of extract .The concentrations (750 ,1000)µg/ml were used in following immunological experiments .The immunomodulatary activity was determined in vitro assays with using activated mouse (males type BALB/c) macrophages and lymphocytes by using lymphoproleferation and reduction of NBT stain .These results indicate that concentration of (750 ,1000) µg/ml inhibited The proliferation not due cell toxicity (0.2, 0.1) respectively ,in comparison with negative and positive control(0.3 , 1.6) respectively .The results of NBTwere indicated the significant inhibition (without cytotoxicity ) in the percentage of PMNLs forming Formazan granules which were (29.4 , 15.2) in comparesion with control(43.1).deferent | ||
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