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Effect of myristica fragrans L. seed extracts on the fertility of male albino mice and some functional parameters | ||
| journal of al-qadisiyah for pure science(quarterly) | ||
| Article 1, Volume 9, Issue 1, 2009, Pages 1-7 PDF (0 K) | ||
| Author | ||
| Tahreer M.natah | ||
| Abstract | ||
| The work aimed to study the effect of aqueous and alcoholic extracts of Myristica fragrans L. seeds on the fertility of males of albino mice. Fourty Swiss male mice of Balb/C srain were used in this study, for age 50-75 day,and in average 25-35 gm,the mice were divided randomaly into control group and treated group and in average 8 for each group,Two doses were used 50 and 100 mg/kg for aqueous extract,25and 50 mg/kg for alcoholic extract, and the animals were injected subcutaneous for 6 weeks as one dose every 48hr, while the mice of the control group were injected with (NaCl 0.9%) normal saline in the same way. Treatment with Myristica fragrans L. extract led to not found significant effect (p>0.05) in the average of testicular weight after the treatment with the extract of Myristica fragrans and average of epididymal weight after the treatment with the aqueous extract 50 and 100 mg/kg,while asignificant decrease (p<0.05) in the average of epididymal weight after treatment with the alcoholic extract 25and 50 mg/kg. significant decrease(p<0.05) in average of percentage of fetal sperm in the testis after treatment with the aqueous extract 50 and 100 mg/kg, and not found significant effect(p>0.05) after treatment with alcoholic extract 25and 50 mg/kg, while a significant increase (p<0.05) in average of percentage of fetal sperm in epididymis after treatment with extracts of Myristica fragrans ,and not found significant effect (p>0.05) in average of percentage of abnormal spermatozoa in epididymis after treatment with extracts of Myristica fragran | ||
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