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Study The Effect of different Concentration of Prostaglandin F2α in the male reproductive System and som of the blood parameters in Albino Mice | ||
| journal of al-qadisiyah for pure science(quarterly) | ||
| Article 1, Volume 9, Issue 1, 2009, Pages 16-28 PDF (0 K) | ||
| Author | ||
| Wejdan Matrood Kadhem AL-Azawy | ||
| Abstract | ||
| The present study was aimed to termine the effect of prostaglandin F2α in the male reproductive system and some of the blood parameters in mice . It was used (18 ) animal , they were divided randomly into three equal groups as follows :- The first group :It was treated with dose of prostaglandin F2α in concentration 10µgkg of body weight . The second group : It was treated with dose of prostaglandin F2α concentration 20 µgkg of body weight . The control group : It was treated with normal saline 0.9% . The results were appeared significant decrease (p<0.05) in the weights of testes and epididymis in animals of two experimental groups as compared with the control groups . While there was significant increase (p<0.05) in the means of The red blood corpuscles count , hemoglobin concentration and packed cell volume in the second experimental group as compared with the control group , and significant decrease (p<0.05) in the mean of total leukocytes count in the first and second groups as compared with the control group . Also these results were showed a significant increase (p<0.05) in the mean of the triglyceride concentration , total cholesterol concentration ,LDL–C and VLDL in animal's serum of two experimental groups in compar ison with the control group . The histological study of the animals testes was showed degeneration and necrosis in some of somniferous tubules with a decrease in spermatogenesis and an increase in the distance between the somniferous tubules in the second experimental group in comparison with the control group . The histological changes in the epididymal tissues were showed irregular arrangement of endometrial lining cells of epididymal tubule with a decrease in the mature sperm | ||
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