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Serum Lipid Profile In Type 2 Diabetes Mellitus In Male and Females: More Atherogenic Lipid Profile In Postmenopausal females | ||
| journal of al-qadisiyah for pure science(quarterly) | ||
| Article 1, Volume 9, Issue 1, 2009, Pages 14-22 PDF (0 K) | ||
| Author | ||
| Rasha S. Nema | ||
| Abstract | ||
| In the present study we evaluated serum lipids profiles alteration in the type 2 diabetic males and females with fair to good controls, in addition we compared the level of serum lipid profiles in diabetic males with that of diabetic females, and the level of serum lipid profiles in diabetic premenopausal with that of their diabetic postmenopausal counter parts. To achieve this aim, 112 type 2 diabetic patients and 100 age matched healthy individuals with normal glucose tolerance test (control groups) including in this study. These patients and controls subject were classified as male(58 patients ,50 controls), females (54 patients ,50 controls) . Females then subdivided into premenopausal females(27 patients ,25 controls) and postmenopausal females(27 patients ,25 controls) .Body mass index and clinical tests including serum lipoproteins were measured for patients and controls. The results revealed significant (p<0.001) elevation of serum total cholesterol, triglycerides ,LDL- cholesterol , VLDL- cholesterol , except HDL-cholesterol which is decreased significantly (p<0.001), in all diabetic patients when compared with those of control groups. Females patients had higher level (p<0.05), of BMI , total cholesterol triglycerides, LDL-cholesterol, VLDL- cholesterol and low HDL- cholesterol (p<0.05), compared to age matched male patients. However, there was no significant difference in the total cholesterol and the triglycerides between the diabetic premenopausal ,and postmenopausal females (P>0.05). and a significant reduction in the level of HDL –cholesterol and VLDL-cholesterol in the postmenopausal group, and significant increase in the vale of LDL- cholesterol(P<0.05).The results pointed out, that the sex was not an independent risk factor for hyperlipidemia,in addition, diabetic postmenopausal females are more prone for hyperlipidemia than diabetic premenopausal females, consequently they are more prone of developing Cardiovascular diseases. | ||
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