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Anthropometric, hormonal and biochemical Indices in patients with polycystic ovarian syndrome | ||
| Iraqi Journal of Embryos and Infertility Researches | ||
| Article 1, Volume 3, Issue 6, 2013, Pages 15-20 | ||
| Authors | ||
| Anam R. Al-Salihi; Farqad B Hamdan; Manal T Mutib | ||
| Abstract | ||
| Background: Polycystic ovary syndrome is the most common, yet complex, endocrine disorder with principal features of anovulation, amenorrhea, ovulation-related infertility, polycystic ovaries, and obesity. Number of metabolic aberrations is now well recognized as a growing public health problem in PCOS as glucose intolerance, hyperinsulinemia and dyslipidemia. Objective: To investigate and analyze the anthropometric, hormonal profileandmetabolicabnormalitiesofobeseand non-obese women with this disorder. Materials and Methods: Sixty-fivehealthyIraqiwomenservesasthecontrolgroupandeighty-fourinfertilewomendividedinto two subgroups depending on the BMI (< and ≥30 kg/m2) were studied. BMI, waist to hip ratio and waist to thigh ratio were measured. Serum levels of luteinizing hormone, follicle stimulating hormone, estradiol, testosterone, fasting blood glucose, and oral glucose tolerance test, and total lipid profilewere measured. Results: BMI, waist/hip, waist/thigh ratio were significantlyhigherinPCOSthancontrolwomen.LowerFSHlevel, higher LH and E2 levels, LH/FSH ratio, and lower E2/testosterone ratio was found in obese and non-obese PCOS. Higher blood sugar level, high cholesterol, triglyceride, LDL, VLDL and lower HDL levels in PCOS compared to control women. Conclusion: Obesity is a common findingofwomenwithPCOS,butitisnotpartofthediagnosticcriteria.Womenwith PCOS usually have the so-called central obesity (Visceral adiposity), and therefore tend to have an increased waist-hip ratio (WHR) and waist to thigh ratio, regardless of the weight factor (i.e., in obese and non-obese). PCOS patients exhibited abnormal hormonal status and biochemical indices also regardless of obesity. | ||
| Keywords | ||
| PCOS; Obesity; Hormones; GTT; Lipid profile | ||
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