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Preparation and evaluation of the anti-bacterial Activity for some Formazans | ||
| karbala journal of pharmaceutical sciences | ||
| Article 1, Volume 6, Issue 10, 2015, Pages 0-0 PDF (0 K) | ||
| Authors | ||
| Ibtisam K. Jassim; Fawzi H. Jumaa; Omar M. AbdulMuhsin | ||
| Abstract | ||
| In the present research, a series of Formazans derivatives 7a-j have been prepared by the condensation of Schiff bases (4,5) and diazonium salt of substituted aromatic amines Heterocycl, 6a-e. The intermediate Schiff bases (4,5), was itself synthesized by condensation of2- amino benzothiazole (1), with 4-nitro and dimethylamino benzaldehyde, (2,3). All the reaction were routinely monitored and purity was determind on thin layer chromatography using coated aluminum plates and spots were visualized by exposing the dry plates in iodine vapours.The structures of the compounds have been confirmed by , Mass spectroscopy 1H NMR, U.V, IR spectral data and melting points. The antibacterial activity of the compounds has also been screened. | ||
| Keywords | ||
| formazans; diazonium salt; Schiff bases; Antimicrobial activity | ||
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