8.LEVELS OF TUMOR NECROSIS FACTOR ALPHA AND INTERLEUKIN-17 IN FERTILE AND INFERTILE WOMEN WITH ENDOMETRIOSIS

S.A. Al-Azawy, Vean

	8.LEVELS OF TUMOR NECROSIS FACTOR ALPHA AND INTERLEUKIN-17 IN FERTILE AND INFERTILE WOMEN WITH ENDOMETRIOSIS
IRAQI JOURNAL OF MEDICAL SCIENCES
Article 1, Volume 15, Issue 2, 2017, Pages 159-164
Author
Vean S.A. Al-Azawy
Abstract
Background: Endometriosis is described by the existence of endometrial tissue outside the uterine cavity. Infertility is one of clinical manifestation of endometriosis shown by the difference of fecundity. Objective: To compare the serum levels of TNF-α and IL-17 in fertile and infertile endometriosis patients. Methods: This study was conducted on 55 women patients with endometriosis (30 infertile women and 25 fertile women) and twenty apparently healthy controls. The technique used to reveal serum level of TNF-α and IL-17 was Enzyme-linked immune sorbent assay (ELISA). Results: This study revealed significant increase (p<0.05) in serum levels of TNF-α in infertile patients other than that fertile. On the other hand, there were no significant differences (p>0.05) between controls and each group of patients. Moreover, there were significant increase (p<0.05) in IL-17 levels in infertile patients than that fertile patients and controls, while there were no significant differences (p>0.05) between fertile patients and controls. Conclusion: The current results indicate that TNF-α and IL-17 might play a crucial role in endometriosis-related infertility. Keywords: Endometriosis, TNF-α, IL-17. Citation: Vean S.A. Al-Azawy. Levels of tumor necrosis factor alpha and interleukin-17 in fertile and infertile women with endometriosis. Iraqi JMS. 2017; Vol. 15(2): 159-164 . doi: 10.22578/IJMS.15.2.8
Keywords
Endometriosis; TNF

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