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Study theeffect ofTamoxifenon Lipid profilein Male Albino Rats | ||
| Iraqi Journal of Science | ||
| Article 1, Volume 58, Issue 4, 2018, Pages 1815-1819 | ||
| Authors | ||
| Aqeel H. Qasim; Abed H. Baraj | ||
| Abstract | ||
| Tamoxifen(TAM) is an effective anticancer drug. This study was conducted to evaluate the side effects of Tamoxifenon the lipid profile. 40 rats divided into 4 equal groups,3 groups were given different doses (30, 40, 50)mg/kg body weight of TAM three times a week for 8 weeks as well as control group that was given with physiological solution.At the end ofexperiment, The results showed significant differences in the treated groups were the results showed a significant degrees (p<0.05) in the HDL level in the treatment group (50mg/kg) while the three groups showed a significant increase in the levels of (Ch, TG, LDL, VLDL). The results of the study showed that Tamoxifen caused an accumulation in fats. | ||
| Keywords | ||
| Tamoxifen; Albino rats; Lipid profile | ||
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