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Assessment of Omentin-1 as a predictor and Renoprotective for type 2 Diabetic Nephropathy | ||
| IRAQI JOURNALOF COMMUNITY MEDICINE | ||
| Article 1, Volume 30, Issue 1, 2017, Pages 19-24 | ||
| Authors | ||
| Isam Noori Al-Karawi; Sarah Salim Mohammed Al-Fahdawi | ||
| Abstract | ||
| Background: Diabetic nephropathy is one of the most serious microvascular complications of diabetes, which may lead to chronic kidney disease in diabetic patients. Objective: to explore correlation of omentin-1 and diabetic nephropathy in type 2 diabetic patients. Method: Serum omentin-1 levels were measured by enzyme-linked immunosorbent assay (ELISA) in 61 type 2 diabetic patients. These patients were classified into two groups according to their albumin/creatinine ratio (ACR), into patients with normoalbuminuria, group C (ACR< 30 mg/mmol), patients with microalbuminuria, group B (ACR=30-300 mg/mmol), twenty five (25) (10 male and15 female) apparently healthy matching the Pearson were selected as a control group (group A).In addition, glucose and lipid profile and morphological characters were assessed. Result: The serum OMT level of group B was much lower than those of group C and group A. While, there was non-difference in OMT level between group C and group A. Conclusion: Detection of serum OMT level may play an important role in early diagnosis and prevention of diabetic nephropathy in T2DM. | ||
| Keywords | ||
| diabetic nephropathy; omentin; adipose tissue | ||
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