A. Nief, O., N. Salman, H., S. Ahamed, L. (2017). Synthesis, Characterization, Biological Activity Studies of Schiff Bases and 1,3-Oxazipene Derived from 1,1 -Bis (4-aminophenyl) -4-Phenyl Cyclohexane. , 58(4), 1998-2011.
Olfat A. Nief; Hussein N. Salman; Luma S. Ahamed. "Synthesis, Characterization, Biological Activity Studies of Schiff Bases and 1,3-Oxazipene Derived from 1,1 -Bis (4-aminophenyl) -4-Phenyl Cyclohexane". , 58, 4, 2017, 1998-2011.
A. Nief, O., N. Salman, H., S. Ahamed, L. (2017). 'Synthesis, Characterization, Biological Activity Studies of Schiff Bases and 1,3-Oxazipene Derived from 1,1 -Bis (4-aminophenyl) -4-Phenyl Cyclohexane', , 58(4), pp. 1998-2011.
A. Nief, O., N. Salman, H., S. Ahamed, L. Synthesis, Characterization, Biological Activity Studies of Schiff Bases and 1,3-Oxazipene Derived from 1,1 -Bis (4-aminophenyl) -4-Phenyl Cyclohexane. , 2017; 58(4): 1998-2011.

Synthesis, Characterization, Biological Activity Studies of Schiff Bases and 1,3-Oxazipene Derived from 1,1 -Bis (4-aminophenyl) -4-Phenyl Cyclohexane

Iraqi Journal of Science
Article 1, Volume 58, Issue 4, 2018, Pages 1998-2011
Authors
Olfat A. Nief; Hussein N. Salman; Luma S. Ahamed
Abstract
A series of new Schiff bases and 1, 3-Oxazepine derivatives have been synthesised from condensation compound (1,1 -bis (4-aminophenyl) -4-phenyl cyclohexane [C1] with different aromatic aldehydes in the presence of catalytic glacial acetic acid to produce the Schiff bases [2-4]. These Schiff bases were reacted with maleic anhydride and phthalic anhydride in dry benzene to give seven-membered heterocyclic ring derivatives [5-10]. The structure formula of these compounds were confirmed by using FT-IR, (1H and 13C) NMR spectroscopy. The synthesized compounds were screened for their anti‐bacterial activity using ampicillin as a standard drug.
Keywords
Schiff bases; oxazepine; Diamine aromatic compound; antibacterial activity
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