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Toxopathological changes induced by high doses of sustanon in male rats treated with Alpha lipoic acid | ||
| Al-Anbar Journal of Veterinary Sciences | ||
| Article 1, Volume 10, Issue 1, 2017, Pages 58-64 PDF (1.93 M) | ||
| Authors | ||
| Kh. H. Aljeboori; A. B. Majhool | ||
| Abstract | ||
| This study was designed to evaluate the toxopathological effect of high doses of anabolic androgenic steroid (sustanon) in male rats and under the effect of alpha lipoic acid (ALA). Three groups of male rats (20 rat each group) were treated with I.M injection of sesam oil (control group) and 20 mg/kg.b.wt. Sustanon-sesam oil I.M (2nd group) and 3rd group, I.M treated with sustanon-sesam oil as a 2nd group and orally giving ALA 10mg/100gm b.wt. weekly for 60 days. The results showed extensive to maderate histopathological lesions including degenerative changes and inflammatory cellular reaction in the 2nd group and in the 3rd group respectively after 30th and 60th days. In conclusion the extensive to moderate histopathological degenerative and inflammatory cellular response in male rats treated with high doses of sustanon-sesam oil and sustanon- sesam oil alpha lipoic acid | ||
| Keywords | ||
| Toxopathological; sustanon; Alpha lipoic acid; Male rats | ||
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