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Effect of Different Purified Pseudomonas exopigments on Vero-Cell Line and Some Pathogenic Bacterial Isolates | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 14, Issue 3, 2017, Pages 525-531 | ||
| Authors | ||
| Zainab Adil Ghani Chabuck; Maysa Salih Al-Shukri; Lamees A. Abdul-Lateef | ||
| Abstract | ||
| Genus Pseudomonas includes different species, each has the ability to produce different types of characteristic exopigments with their various manners of activities. This study includes production of Pseudomonas pigments like Pyocyanin and fluorescin in liquid culture media and used to examine their antibacterial activity. Also their cytotoxic effects on normal cell (Vero cell line) were used in vitro. The results revealed that pyocyanin pigment has growth stimulatory effect on vero-cell line caused increase in the growth of the cells number, especially at a concentration 30-40%, while fluorescin has cytotoxic inhibitory effect on vero-cell line causing inhibition in growth of the cells number, the inhibition ranged from 55-75%, especially at a concentration 30-40%. Pseudomonas exopigments are effectual antigrowth agents against different bacterial isolates, as well as human cells lines. | ||
| Keywords | ||
| Pseudomonas; Pyocyanin; Fluorescin; Vero cells; HPLC | ||
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