THE POSSIBLE ASSOCIATION BETWEEN THE DEGREE OF FAMILY HISTORY AND INSULIN AUTOANTIBODIES (IAAS) LEVEL IN DIABETIC PATIENTS +

Majid Jameel, Yousor

	THE POSSIBLE ASSOCIATION BETWEEN THE DEGREE OF FAMILY HISTORY AND INSULIN AUTOANTIBODIES (IAAS) LEVEL IN DIABETIC PATIENTS +
AL-TAQANI
Article 1, Volume 26, Issue 3, 2013, Pages 0-0
Author
Yousor Majid Jameel
Abstract
The aim of this study was to find out the possible association between insulin autoantibodies (IAAs) level in diabetic patients and the degree of relativeness in the family history of diabetes mellitus. Two groups samples were included in the study; the first was one hundred and one diabetic persons (type 1 and 2 diabetes mellitus) representing the patients group, and thirty five healthy persons representing the control group. The patients’ group was further divided into four subgroups according to the degree of diabetic relatives in the family history, twenty three of first degree diabetic relatives (22.7%), twenty four of second degree of diabetic relatives (23.7%), eighteen of first and second degree diabetic relatives (17.8%), and thirty six of no degree diabetic relatives (35.6%) of the family history of the disease. Insulin autoantibodies were measured in all patients’ subgroups by immuno radio metric assay (IRMA) technique. Data analysis showed an association between the degree of diabetic relatives of family history and the IAAs mean level in all patients’ subgroups; in comparison with the control group with a statistically significant difference. This result might conclude that IAAs level in diabetic patients is possibly associated with the degree of diabetic relatives within the family history
Keywords
Diabetes Mellitus; DMT; IAAs; Family History; Degree Relatives

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